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研究表明，动物会思考概率区分上下文

新的统计模型可以帮助科学家了解动物如何推断环境是否是新的还是没有改变足以成为一个新的上下文。

2020年8月12日

MIT neuroscientists have linked the vulnerability of neurons in Hungtington's disease to the release of mitochondrial RNA and an associated immune system response. In this image, on the right are neurons from a Huntington's model mouse showing much more PKR (a marker of immune response to mitochondrial RNA) in green than neurons on the left, which are from a healthy mouse.

在亨廷顿氏病的神经脆弱性依赖于线粒体RNA释放

在人类和小鼠细胞类型的基因表达的独特调查显示影响最脆弱的神经元数的赤字。

2020年7月21日

The left side shows a "tonic" neuron (stained green) growing to just one muscle on the right of the panel. In the next panel, one can see a "phasic" neuron (also stained green) connecting to more than one muscle.

看似相似，两个神经元表现出截然不同的风格，因为他们具有相同的肌肉伙伴互动

多样性细胞如何跟他们支配揭示变化不同的倾向，或肌肉“可塑性”。

二〇二〇年七月二十○日

Within a microscope image of neurons from the hippocampus region of a rodent brain (left), a zoomed-in section (red square) of a neuron's dendrites shows spines (right) where many synaptic connections with other neurons reside.

调查结果削弱概念，即大小等于神经连接强度

研究的诸多惊喜中可能是解决脆性X综合征的新方式 - “蛋白质X”找到一个

2020年7月14日

Using a new kind of microscope that closely tracks every movement, researchers seeking to study how organisms coordinate movement behaviors compiled a compendium of 100 reference postures that encompass the range of typical C. elegans poses.

蠕虫如何运动：多巴胺有助于线虫协调运动行为

对蠕虫连日间谍，皮考尔研究所的科学家发明了一种新的开源平台显微镜。

2020年6月30日

When keeping track of location a particular region of the brain, the lateral septum, pays special attention to where the reward is located, compared to another region, the hippocampus, that tracks location without that same bias.

就像藏宝图，大脑区域强调奖励位置

横向隔编码与特别强调在奖励所在的空间信息。

2020年6月23日

In Alzheimer's disease, the blood-brain barrier can become disrupted by the accumulation of amyloid protein, especially in people who carry a genetic variant called APOE4. This 3D rendering of an APOE4-carrying engineered blood vessel shows heavy accumulation of amyloid protein (green).

研究发现路径解决阿尔茨海默血脑屏障功能障碍

MIT的研究人员精确机制，并证明药物可以帮助。

2020年6月15日

研究ers are studying the role of the immune system molecule IL-6 in Huntington's disease, which leads to neurodegeneration in a region of the brain called the striatum. In this figure from a prior study, green staining highlights Stat3 in the striatum. Stat3 is a major transducer of IL-6 signaling.

研究亮点亨廷顿氏病的免疫分子的复杂的角色

在高清模型小鼠敲除免疫细胞因子IL-6加重症状，影响神经连接的基因。

2020年6月8日

A new technology called ELAST transforms tissues, such as this slab of human brain, to make them reversibly stretchable or compressible, as well as much more durable. This allows them to be repeatedly stretched out or squished down thin for much faster infusion of labeling probes, which labs use to highlight cells or molecules under the microscope.

使组织拉伸，压缩，几乎坚不可摧

所谓ELAST化学过程使标记探针更迅速地注入，使样品不够强硬的反复操作。

2020年5月20日

MIT scientists have identified a potential new strategy for treating Fragile X syndrome, a disorder that is the leading heritable cause of intellectual disability and autism. The team includes, from left–right: Amanda Coranado, Arnold Heynen, Mark Bear, Rebecca Senter, Laura Stoppel, and Patrick McCamphill.

科学家发现逆转脆性X症状的新途径

药物化合物，在小鼠中测试，可以有效地治疗智力障碍和孤独症的主导遗传原因。

2020年5月20日

In this figure, neurons in the bottom row, which are missing the HDAC1 gene, show higher levels of DNA damage (green) than normal neurons.

研究发现，神经细胞老化积累的DNA损伤

重新激活，促进DNA修复酶可以帮助小鼠扭转与年龄有关的认知衰退。

2020年5月18日

MIT researchers have found that a protein called SYT7 appears to limit activity at neural connections called synapses. Here, synapses glowing light green are engaged in neurotransmitter release.

研究发现，“音量旋钮”车削神经交流向上或向下

蛋白质突触结合蛋白7中的限制供给含有神经递质的囊泡的释放在突触。

2020年5月13日

Mounting evidence suggests that the SARS-CoV-2 virus affects the brain, as well as the lungs.

怎么可能covid-19和机体的免疫反应影响大脑？

皮考尔研究所的研究人员正在着手进行实验，以了解由冠状病毒可能会影响心理健康的机制。

2020年4月28日

“I’m grateful that I have skills to contribute during this time when the hospital needs our help and patients need our help,” says Picower Institute researcher and Massachusetts General Hospital neurologist Diane Chan, who has been helping evaluate patients in respiratory illness clinics during the coronavirus pandemic.

covid-19电话bt365手机app的医生，科学家一线呼吸护理

在帮助新英格兰神经学家和研究员陈黛安球场度过艰难时期。

2020年4月22日

MIT Senior 研究 Associate Kendyll Burnell and her poodle Soma examine neural imaging data together at home during the Covid-19 pandemic.

从家里研究：科学保持社会，甚至在距离

尽管时间皮考尔研究所的研究人员正在推进其在许多方面的工作从实验室走需要畜栏covid-19。

2020年4月7日

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